Nature

Copy number variants of schizophrenia susceptibility loci are associated with a spectrum of speech and developmental delays and behavior problems

Purpose: Recently, molecular cytogenetic techniques have identified novel copy number variants in individuals with schizophrenia. However, no large-scale prospective studies have been performed to ...
Nature

Clinical relevance of small copy-number variants in chromosomal microarray clinical testing

The 2010 consensus statement on diagnostic chromosomal microarray (CMA) testing recommended an array resolution ≥400 kb throughout the genome as a balance of analytical and clinical sensitivity. In ...
Science Daily

New Method Developed To Detect Copy Number Variants Using DNA Sequencing Technologies

Researchers have developed a sensitive and accurate way of identifying gene copy number variations. The method uses new DNA sequencing technologies to look for regions of the genome that vary in copy ...
technologynetworks

CSHL Scientists Develop Method to Detect Copy Number Variants Using DNA Sequencing Technologies

A research team led by Associate Professor Jonathan Sebat, Ph.D., of Cold Spring Harbor Laboratory (CSHL) has developed a sensitive way of identifying gene copy number variations (CNVs). The method, ...