Research headed by teams at the University of Rochester Center for Translational Medicine and the University of Copenhagen describes for the first time how a spreading wave of disruption and the flow ...

Cybersecurity leaders are constantly on the hunt for tools and strategies to navigate the complex landscape of digital threats. But despite consistently being held accountable for safeguarding digital ...

Problems with the brain's waste clearance system could underlie many cases of dementia and help explain why poor sleep patterns and cardiovascular risk factors such as high blood pressure increase the ...

The blood-brain barrier prevents xenobiotics from entering the central nervous system. Growing evidence indicates that neurotoxins, such as tributyltin, manganese and nanoparticles, may disrupt the ...

Researchers have discovered, in rodents, that fluid that circulates through the brain flows to areas critical for normal brain development and function, suggesting that disruptions to its circulation ...

A newfound "protective shield" in the brain helps clear waste from the organ and serves as a sentry tower for watchful immune cells that monitor for signs of infection, scientists reported in a study ...

The brain floats in a sea of fluid that cushions it against injury, supplies it with nutrients and carries away waste. Disruptions to the normal ebb and flow of the fluid have been linked to ...

Results showed CNS target engagement with reduction in GCase substrate glucosylsphingosine (GluSph) in cerebrospinal fluid (CSF), a prespecified ...

Diagnostic testing of CSF for surrogate disease markers (i.e., 14-3-3 and total tau) assumes that the patient had a history of acute dementia but did not have several conditions that might compromise ...

NOVATO, Calif., Feb. 06, 2024 (GLOBE NEWSWIRE) -- Ultragenyx Pharmaceutical Inc. (NASDAQ: RARE) today announced data demonstrating treatment with UX111 (ABO-102) AAV gene therapy resulted in rapid and ...