Here we present HiC-DC, a principled method to estimate the statistical significance (P values) of chromatin interactions from Hi-C experiments. HiC-DC uses hurdle negative binomial regression account ...
Genome-wide approach identifies a novel gene-maternal pre-pregnancy BMI interaction on preterm birth
In the discovery sample, we performed frequentist association tests with SNPTEST software (see Methods), and identified that rs149014416, an imputed SNP near 8p12, was genome-wide significantly ...
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