The human genome encodes over 400 ion channels involved in various biological functions 1. Channel inhibitors such as the anesthetic lidocaine 2, the anticonvulsant agent levetiracetam 3, the ...
Mutant MGMT genes encoding O 6 BG-resistant proteins have been included in retroviral vectors as chemoselectable markers for transduced cells. 4, 5 Although MGMT-mediated chemoselection can ...
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